Array Designer 4.25 Build 42501 Download

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Array Designer
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  • Name:Array Designer
  • License:Demo
  • Developer:PREMIER Biosoft International
  • Downloads:49
  • Rating:2 / 5
  • OS:Windows All
  • Size:46.6 MB
  • D.M.C.A. 
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Array Designer 4.25 Build 42501

Array Designer 4.25 Build 42501 Description:

Array Designer designs thousands of primers and probes for oligo and cDNA microarrays in seconds. Array Designer designs probes for SNP detection, microarray gene expression and gene expression profiling. In addition, comprehensive support for tiling arrays and resequencing arrays is available.

Array Designer designs highly specific oligos by interpreting the results of a BLAST search performed against any genomic database available at NCBI or a local custom database. Any significant homologies identified are automatically avoided while designing oligos. Repeat regions are identified and automatically avoided.

You can design primers and probes for SNP detection and gene expression profiling on multiple sequences in a single search run. Our customers, typically choose over 10,000 sequences at a time.

With Array Designer you can study the genetic make-up of entire organisms effortlessly by detecting every gene or exon in the whole genome. This enables easy discovery of differentially and alternatively spliced transcripts, SNPs, DNA sequence variation in individuals or populations and comparative genome hybridization (CGH).

You can spot every base of a long genomic sequence also known as whole genome amplification, avoiding repetitive regions. Designing arrays to characterize regulatory elements, or to study epigenetic modifications, methylation patterns and protein binding sites has never been so easy.

Array Designer designs resequencing arrays with which you can detect SNP and other sequence variations in a large number of samples. One of the common problems in resequencing array design is false base calls caused by inter-template cross hybridization. With the unique feature which we call project BLAST, you can identify and avoid the homologous regions that create false positives.

Array Designer 4.25 Build 42501 Features:

Probe and primer design
· Choices in probe design: Array Designer can design single or multiple probes per sequence for your microarray projects. Allows specifying the minimum distance between two probes to avoid overlapping.
· Product Location: Allows specifying the product (amplicon) length and product location viz at the 3'end, 5'end or anywhere in the sequence.
· Comprehensive selection criteria: Screens oligos for their thermodynamic properties as well as secondary structures. Graphics for the structures are also displayed.
· Ranking: Uses statistical optimization techniques to design the best primer and probe for each template. A list of alternate designs is also available.
· Algorithm: Calculates oligo Tm using nearest neighbor thermodynamic algorithm.

BLAST search
· Specificity Check: Thousands of searches are submitted automatically. Results are interpreted and displayed in the Homology Avoidance window.
· Batch Sequence BLAST search: Array Designer can BLAST search hundreds of sequences. The results are interpreted and the homologies identified are avoided while designing primers.
· Local BLAST: Array Designer can BLAST search against a custom local database that can be set up on a Unix machine using the WWW Standalone BLAST facility of the NCBI. Read the inbuilt product help for details.
· Desktop BLAST: BLAST search sequences against local custom databases without the need of setting up a server on a separate machine. Simply save the sequence files (.txt or .fa) on your computer and ask Array Designer to BLAST search your query sequence against them.
· Verification of specific design: The primers and probes designed by the program can be BLAST searched against all the nucleotide databases available at NCBI to verify the specificity of design.
· Repeat regions: Optimizes BLAST search parameters to detect human repeats while searching the human RNA (previously called mRNA) database at NCBI.

SNP detection & SNP genotyping
· SNP loading: Easily add a single SNP at a time or load thousands of SNPs using standard GenBank variation files.
· SNP Detection: Designs probes for SNP detection (both wild and mutant) with SNP at the center of the probe.
· SNP genotyping with Array Designer: Designs SNP genotyping probes with SNP or one base upstream of the 3' end of the probe.

Whole genome array
· By length: Probes can be designed for the fragments of a size chosen by the user. The sequence is broken down into small equal-sized fragments and then a specific probe is designed for each one of them.
· By position: Probes can be designed on genes/fragments, the start and stop position for which can be imported from a text file.
· By annotation: Probes can be designed on genes or exons, the annotations for which can be read from the GenBank file.
· BLAST to ensure specificity: For a whole genome sequence, Array Designer automatically creates a local custom database of the input sequence and BLAST searches every fragment against it. To verify the specificity of design, you can BLAST the designed oligos.
· Sequence size: Array Designer can design probes spanning the entire genome of the organism. This ability is especially useful to study the expression of intergenic and intragenic regions. Fragments to be studied can be generated on the basis of their length, their position or by specifying an annotation such as gene, exon or both.
· Uniform Tm values: Array Designer designs probes free of secondary structures and with uniform Tm values ensuring a high rate of success of microarray experiments.

Tiling arrays
· Sequence size: Array Designer can design tiling primers to study protein binding regions of small to medium sized genomes. You can generate both distinct or overlapping amplicons depending on the specificity desired.
· Distinct amplicon: Primers are designed such that there is no overlap between adjacent amplicons.
· Overlapping amplicon: Primers are designed such that the adjacent amplicons overlap each other in the flanking regions.
· Whole Genome Amplification using Array Designer

Resequencing arrays
· Resequencing probe design: In addition to standard probes, Array Designer also designs resequencing arrays. With custom resequencing arrays, you can detect SNP and other sequence variations in a large number of samples for applications such as biowarfare pathogen studies, bacterial identification, predisposition and resistance to disease or discovering the genetic basis of phenotypic traits.
· BLAST search: The challenge in designing chips for resequencing by hybridization is to achieve the lowest possible false positive rate. Array Designer offers an innovative and unique project BLAST capability to identify these regions and recommends a multi-chip solution.
· Avoiding repetitive regions: You can simply connect to the popular Repeat Masker using the handy link and Array Designer will avoid creating spots that may generate false positives.

Array Designer 4.25 Build 42501 Requirements:

· CPU Pentium IV
· RAM 256 MB of available
· Hard Disk Drive Space 500 MB of available
· Screen Resolution 800 X 600 1024 X 768

Array Designer 4.25 Build 42501 Limitations:

· Fully demonstrates every function and feature of the product, but limited to the sample data provided.

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Array Designer security information

You cannot download any crack or serial number for Array Designer on this page. Every software that you are able to download on our site is legal. There is no crack, serial number, hack or activation key for Array Designer present here. Our collection also doesn't contain any keygens, because keygen programs are being used in illegal ways which we do not support. All software that you can find here is freely downloadable and legal.

Array Designer installation package is prepared to be downloaded from our fast download servers. It is checked for possible viruses and is proven to be 100% clean and safe. Various leading antiviruses have been used to test Array Designer, if it contains any viruses. No infections have been found and downloading Array Designer is completelly problem free because of that reason. Our experts on malware detection tested Array Designer with various spyware and malware detection programs, including custom malware and spyware detection, and absolutelly no malware or spyware was found in Array Designer.

All software that you can find on our servers, including Array Designer, is either freeware, shareware or open-source, some of the software packages are demo, trial or patch versions and if possible (public domain licence), we also host official full versions of software.

Because we want to be one of the fastest download sites on the web, we host all the software including Array Designer on our servers. You cannot find here any torrents or download links that would lead you to dangerous sites. does support free software, however we do not support warez or illegal downloads. Warez is harming producers of the software.


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