RDM Circles 0.1.1 Download

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RDM Circles
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  • Name:RDM Circles
  • License:Freeware
  • Developer:Roderic D. M.
  • Downloads:49
  • Rating:2 / 5
  • OS:Windows All
  • Size:1.3 MB
  • D.M.C.A. 
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RDM Circles 0.1.1

RDM Circles 0.1.1 Description:

The RDM Circles application was designed to be an experimental Windows program for inferring RNA secondary structure using the comparative method.

Comparative analysis is the preferred method of inferring RNA secondary structure, but its use requires considerable expertise and manual effort. As the importance of secondary structure for accurate sequence alignment and phylogenetic analysis becomes increasingly realised, the need for secondary structure models for diverse taxonomic groups becomes more pressing.

Maximum weight matching (MWM) is graph-theoretic approach to inferring RNA secondary structure that shows considerable promise. It takes as input a set of base pairing scores that can be derived from a range of sources, such as free energy considerations, mutual information, or experimental data.

These data can be represented as a folding graph where the vertices are alignment positions, and the lines or edges connecting a pair of vertices are given a weight proportional to the amount of evidence for that pairing. A matching is a subgraph of the folding graph in which no vertex is connected to more than one other vertex.

The matching with the greatest total edge weight is the taken to be the best estimate of the RNA structure. This matching can include information on both secondary and tertiary structure, such as pseudoknots. MWM can greatly speed up the process of comparative structure analysis of RNA sequences, and has been tested successfully on tRNA, SRP RNA, and 16S rRNA sequences.

RDM Circles security information

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RDM Circles installation package is prepared to be downloaded from our fast download servers. It is checked for possible viruses and is proven to be 100% clean and safe. Various leading antiviruses have been used to test RDM Circles, if it contains any viruses. No infections have been found and downloading RDM Circles is completelly problem free because of that reason. Our experts on malware detection tested RDM Circles with various spyware and malware detection programs, including fyxm.net custom malware and spyware detection, and absolutelly no malware or spyware was found in RDM Circles.

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Enjoy!

Rate RDM Circles 0.1.1!

Rating: 2.3/5 (9 votes cast)

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